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Sophia Mantel

PhD student

Background

 

I obtained my medical degree from Erasmus University Rotterdam in 2024. During my clinical traineeships, I developed a strong interest in neurology, which led me to work as a resident not in training (ANIOS) in the Department of Neurology at Albert Schweitzer Hospital in Dordrecht.

Since August 2025, I have been pursuing a PhD at the Department of Neurology at Erasmus University Medical Center in Rotterdam.

Research interest

My PhD research focuses on clinical studies aimed at improving the diagnosis, treatment, and monitoring of chronic inflammatory demyelinating polyneuropathy (CIDP).

My main project investigates the use of wearable devices to monitor physical activity in CIDP patients, aiming to determine whether these devices can provide a reliable indication of clinical improvement or decline.

I am also involved in the Rituximab Trial, which examines whether initiating rituximab treatment can reduce relapse rates and improve outcomes in selected patients.

Additionally, I contribute to the CIDP Mimics Study, which collects clinical data from patients with CIDP and related conditions (“CIDP mimics”) to identify novel biomarkers and disease-specific features that may enhance diagnostic accuracy.

Research focus

My research focuses on CIDP.

A list of research articles

  • CIDP Mimics study

    • Study on CIDP

    Background:Chronic inflammatory demyelinating polyneuropathy (CIDP) is a disease of the peripheral nerves. These nerves provide the connection between the brain, the muscles and skin. We do not know exactly how CIDP arises. The idea is that an immune reaction against the nerves arises due to an unknown cause. This causes gradual loss of strength, loss […]

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  • ICOS: International CIDP Outcome Study

    • Study on CIDP

    International CIDP Outcome Study (ICOS) In this study, we investigate the variation and predictors of the disease course in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Background CIDP is a rare condition caused by inflammation of the nerves. This causes complaints of loss of strength and sensory disturbances in the arms and legs. These complaints usually develop […]

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