Sander van Tilburg
PhD student
Background
I obtained my bachelor’s degree in biology and master’s degree in biomedical sciences from Leiden University.
Currently, I work as a PhD student at the Department of Immunology at the Erasmus MC University Medical Centre, closely collaborating with the Department of Hospital Pharmacy and the Department of Neurology at the Erasmus MC.
Research interest
The main goal of my project is to personalize treatment with intravenous immunoglobulin (IVIg) for patients with Guillain-Barré syndrome (GBS) and Chronic Inflammatory Demyelinating Polyneuropathy (CIDP).
To achieve this, we utilize non-linear mixed-effects models (NONMEM), the gold standard for pharmacokinetic and pharmacodynamics studies, to describe and predict concentration-time profiles for individual patients and identify factors that influence how the body handles IVIg.
The aim is to identify patients who respond poorly to the current standard dosing regimen and provide tailored treatment for every patient.