Nadine van der Beek

My background

I was trained as a clinical neurologist at the Erasmus MC in Rotterdam, the Netherlands. Subsequently, I did a further specialization in neuromyology (Erasmus MC /  Hôpital Universitaire Pitié-Salpêtrière in Paris). Since 2014 I am employed as a staff consultant at the department of Neurology at Erasmus MC.

My PhD-research focused on the clinical features of patients with Pompe disease, and the effect of enzyme replacement therapy in this patient group (2013).

I am a current board member of the Spierziekten centrum Nederland, and a co-chair of the muscle working group of the European Reference Network for neuromuscular diseases (Euro-NMD).

My projects

My expertise is the clinical care and research of children and adults with neuromuscular diseases.

Working together closely with a dedicated team of staff and PhD students within the Centre for Lysosomal and Metabolic Diseases (CLMZ), my main research focusses currently on 3 topics:

1. long-term effects of enzyme-replacement therapy in children and adults with Pompe disease
2. validation of new outcome measures
3. translational research into the development of new therapies (a.o. lentiviral gene therapy) for Pompe disease

I was involved in the founding of the European POmpe Consortium (EPOC), leading the work package on outcome measures and registries.