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Bart Jacobs

Group Leader Clinic

My background

I was trained as clinical neurologist and immunologist at Erasmus MC in Rotterdam. My PhD research was about preceding infections, molecular mimicry and anti-ganglioside antibodies in the Guillain-Barré syndrome (GBS). I was a research fellow at the University of Glasgow (Prof. Hugh J. Willison lab).

Since 2003 I am employed as staff consultant at the department of Neurology and as staff work group leader at the department of Immunology of Erasmus MC. In 2015 I was appointed as full professor in Peripheral Nerve Inflammation at Erasmus MC.

 

 

My projects

My expertise is the clinical care and research of patients with inflammatory diseases of the peripheral nervous system. I have a special interest in GBS and chronic inflammatory demyelinating polyneuropathy (CIDP). My projects focus on the epidemiology, pathogenesis, diagnosis, treatment, prognosis and outcomes of these disorders.

 

My laboratory studies focus on the role of molecular mimicry, antibodies, host factors, genetics and biomarkers of GBS and CIDP and on pharmacokinetics. I have coordinated the development of various prognostic models for GBS, including the EGOS, mEGOS, EGRIS, mEGRIS and EGRIS-Kids, that are frequently used in clinical practice.

 

I have initiated the International GBS Outcome Study (IGOS), co-initiated the International CIDP Outcome Study and I am a member of the steering committee of INCbase.