Detecting anti-paranodal antibodies
Date published: March 26, 2025
My research primarily focuses on investigating novel pathogenic antibodies in paranodal regions associated with immune-mediated neuropathies.
The aim of my project is to improve diagnostic methods for detecting anti-paranodal antibodies and to determine the prevalence of these harmful autoantibodies in patients with Guillain-Barré Syndrome (GBS).
A list of research articles
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The role of B lymphocytes in the progression of chronic immune-mediated neuropathies
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Study on CIDP
In addition, I am studying the role of B lymphocytes in the progression of chronic immune-mediated neuropathies, including Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) and Autoimmune Nodopathy (AN). Through this research, we strive to enhance diagnostics, clinical care, and treatment options for patients affected by these conditions.
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Time to treatment study
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Study on GBS
In this project, we aim to describe the current practice of time to treatment. We also assess the association with functional outcome in patients with GBS who received first-line treatment with intravenous immunoglobulin or plasma exchange. This study is performed using data from the International GBS Outcome Study (IGOS).
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PK-PD modelling in patients with CIDP.
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Study on CIDP
The optimal maintenance dosing regimen of intravenous immunoglobulin (IVIg) varies between patients with CIDP. At present, there is only limited information available on the pharmacokinetics (PK) of IVIg treatment in patients with CIDP. In this study we want to describe the PK of IVIg induction and maintenance treatment in patients with CIDP using non-linear mixed […]
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