Current research

• Study on CIDP

Background:Chronic inflammatory demyelinating polyneuropathy (CIDP) is a disease of the peripheral nerves. These nerves provide the connection between the brain, the muscles and skin. We do not know exactly how CIDP arises. The idea is that an immune reaction against the nerves arises due to an unknown cause. This causes gradual loss of strength, loss […]

• Study on GBS

BackgroundGuillain-Barré Syndrome (GBS) is a disorder of the peripheral nerves. These nerves provide the connection between the brain and spinal cord and the muscles and skin. If this connection is damaged by GBS, this leads to serious loss of strength, loss of sensation and pain. GBS is caused by inflammation of these nerves and treatment […]

• Study on CIDP

In addition, I am studying the role of B lymphocytes in the progression of chronic immune-mediated neuropathies, including Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) and Autoimmune Nodopathy (AN). Through this research, we strive to enhance diagnostics, clinical care, and treatment options for patients affected by these conditions.

• Study on GBS

My research primarily focuses on investigating novel pathogenic antibodies in paranodal regions associated with immune-mediated neuropathies. The aim of my project is to improve diagnostic methods for detecting anti-paranodal antibodies and to determine the prevalence of these harmful autoantibodies in patients with Guillain-Barré Syndrome (GBS).

• Study on GBS

In this project, we aim to describe the current practice of time to treatment. We also assess the association with functional outcome in patients with GBS who received first-line treatment with intravenous immunoglobulin or plasma exchange. This study is performed using data from the International GBS Outcome Study (IGOS).

• Study on CIDP

The optimal maintenance dosing regimen of intravenous immunoglobulin (IVIg) varies between patients with CIDP. At present, there is only limited information available on the pharmacokinetics (PK) of IVIg treatment in patients with CIDP. In this study we want to describe the PK of IVIg induction and maintenance treatment in patients with CIDP using non-linear mixed […]